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  • Build Muscle
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  • Summary
  • Side Effects
  • Other Names
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Agmatine Overview

Agmatine is among one of the top dietary supplements that has been made available to body builders and health enthusiasts alike. However, its recent popularity and increased promotion is not necessarily new; the base form of agmatine has been a very popular supplement in the past in regards to sports nutrition.

It is derived from a process called decarboxylation in which the carboxylic acid is carefully removed from the compound arginine, resulting in a by-product of an amino acid called Arginine. Arginine is still found in many health food stores.

Here is some basic information on Agmatine to help you further your learning on this supplement.

Potential Agmatine Side Effects

  • Diarrhea
  • Vomiting
  • Nausea

Other Names for Agmatine

Agmatine guanidine, 4-aminobutyl

Agmatine Nutritional Uses

  • Chronic Pain
  • Insulin Production

Agmatine Dosage

For most people, the usual agmatine dosage consists of 500mg twice daily. Some prefer to take 500mg pre workout, and then another 500mg dose after they finish their routine. Others take the entire dose at one time. Agmatine is readily available in a powder form, and the price varies according to manufacturer.

 However, it is very important to note that there has not been very much literature published on what the appropriate dose is. For this reason, it would probably be beneficial to consult with a qualified professional that has experience with dietary supplements  so that you can skip all of the guess work.

What Agmatine Can Do For You

Agmatine has the potential to improve not only your athletic performance, but also the way you look and feel. Many report that it works even better than the former Arginine supplement in that the effect on both mood and focus are increased.

It has a direct effect on the amount of insulin the body produces, which in turn makes it significantly easier to add lean muscle onto the body. The more lean muscle you have, the harder your body will appear and the more fat it will burn.

Agmatine is also a known antioxidant and it can be found in a number of food items. For instance fish, chocolate, and beef are sources of the naturally occurring state of agmatine. Antioxidants aid the body in shedding unwanted free-radicals that have built up during the course of normal daily activities. 

It contains pain fighting agents as well; however, those can be looked at both in a negative and positive light. For the most part, agmatine has only been shown to help dull the impact of chronic pain. This in turn can boost your workouts by making you more inclined to work.

Since the body naturally produces lower levels of amines as it ages, it might be beneficial for older athletes to supplement their diet with agmatine to help improve both their performance and mental functio

Agmatine Side Effects

Participants in early trials of agmatine did report having some minor abdominal discomfort after they took the supplement. However, all gastrointestinal side effects did stop immediately following the end of treatment. Mild diarrhea, vomiting and nausea were the most commonly experienced effects.

It is also important to note that the ability agmatine has in dulling the pain should be regarded with caution. While it definitely has an upside, the downside to an increased pain tolerance is the fact that you could seriously hurt yourself with the lack of initial pain warning signs. To avoid this, make sure you pay close attention to all of your body’s cues while using any supplement-after all, you have the most intimate knowledge of them.

However, it is very unlikely that agmatine will dull the senses enough to prohibit the body from responding to any new injuries. There has been a study that was able to show that although agmatine lessened the effect of chronic, previously existing pain it had little effect in the way of actually reducing the body’s response to newly established injuries. If you would like to review the study, it was published in the “European Journal of Pharmacology.”

Some Final Words on Agmatine

The positive effects of the amino acid arginine have been known for years. For this reason, it’s easy to deduce that agmatine will also yield the same positive results in all your athletic pursuits. Just keep in mind that no supplement can do all of the work for you- you can’t expect to see results if you don’t put in the required effort. 

Remember to always consult with a physician or trained professional before starting a new regimen, including any dietary supplements you add to your routine. While there have not been any truly negative effects posted on the supplement agmatine, it is always wise to proceed with caution.

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